Effect of low-level laser treatment on cochlea hair-cell recovery after acute acoustic trauma | Laser for hearing tinnitus | laser therapy for hair cell regeneration - Advanced Rejuvenation
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Effect of low-level laser treatment on cochlea hair-cell recovery after acute acoustic trauma | Laser for hearing tinnitus | laser therapy for hair cell regeneration

23 May Effect of low-level laser treatment on cochlea hair-cell recovery after acute acoustic trauma | Laser for hearing tinnitus | laser therapy for hair cell regeneration

Effect of low-level laser treatment on cochlea hair-cell recovery after acute acoustic trauma

Chung-Ku Rhee ; Chan Woong Bahk ; Se Hyung Kim ; Jin-Chul Ahn ; Jae Yun Jung ; Phil-Sang Chung ; Myung-Whan Suh
  • Hearing threshold changes after repeated low-level laser treatment (LLLT). 24 h after noise exposure (after the first LLLT), the ABR thresholds were increased markedly to 50 to 80 dB SPL for both N (noise only) and NL (noise and laser) ears. The hearing threshold between N and NL ears were almost the same until this time point. Signs of change were observed after five days of irradiation. After the 8th to 10th irradiation, a significant difference was found for all frequencies. After the 12th irradiation, the hearing threshold was significantly better on the NL ears when compared to the N ears at all five frequencies. *p<0.05.
  • Representative scanning-electron-microscopic images of the hair cells in the N (noise only) and NL (noise and laser) ears. Missing hair cells (steocilia) were observed throughout the whole cochlea. But more hair cells were missing in N ears when compared to NL ears.
  • Number of hair cells observed by scanning electron microscopy. The number of hair cells of the NL (noise and laser) ears was larger than that of the N (noise only) ears, and this difference was statistically significant in the middle-turn (*p<0.05).The number of hair cells of the C (control) ears was significantly larger than that of the N ears in the apical, middle and the basal turn. The number of hair cells of the C ears was also significantly larger than that of the NL ears in the basal turn. But the number of hair cells of the C ear in the apical and middle-turn was similar to that of the NL ears.

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