When a normal injury occurs, platelets are stimulated to release growth factors, cytokines, and other immune system components, in what is called the inflammatory phase of healing. In the lungs, platelets can adhere to injured or inflamed endothelial cells where they start the healing process. It is believed that by increasing the number of platelets in the lungs through this method of PRP respiratory treatment, it is possible to decrease inflammation and help to accelerate the healing process in the lungs. Platelets are vehicles for the delivery of growth factors (PDGF, TGF-ß, IGF, EGF, VEGF) that induce the proliferation of fibroblasts, osteoblasts, and endothelial cells, promoting and accelerating the healing of hard and soft tissues.
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Autologous Platelet Rich Plasma also contains fibrin, fibronectin, and vitronectin that act as cell adhesion molecules for lung epithelial migration. Autologous Platelet Rich Plasma treatment has been evaluated in various medical disciplines including orthopedics, wound healing, neurosurgery, dentistry as well as cosmetic, plastic, and cardiothoracic surgery. Nebulized Pure PRP treatment holds much promise and is being researched for its applications.
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This new medical advance brings effective and affordable healthcare to many patients with COPD. It is also attractive because the patient’s blood is used, thus limiting the potential for disease transmission.
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Our key product differentiation is to enable the Pure PRP treatment to be applied to patients that are suffering from COPD. COPD affects more than 200 million people across the globe & is a debilitating disease. COPD is considered to be the cause of about 3 million deaths annually. This is a life-threatening disease, caused by various things such as smoking, pollution, dust, irritants, genetic disorders, etc. It is associated with the excess production of sputum and inflammation which obstructs the airways and results in breathing problems.
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Though there is no cure for COPD, the condition can be controlled with the help of treatments. Stem cell therapy which has proved to be one of the most successful treatments for many chronic health conditions like heart diseases, stroke, and osteoporosis, has given a ray of hope in favor of COPD. Stem cells are known for their regenerative properties, which help in the development of tissues and blood cells.  There are two types of stem cells: embryonic stem cells and adult stem cells.  Embryonic stem cells can be derived from blastocyst which is a type of embryo; whereas adult stem cells are found in the bone marrow, skin, umbilical cord, placenta, and many other tissues. Embryonic stem cells are derived and grown in cell culture for research and development. Adult stem cells, once removed from the body, divide with great difficulty, which makes the treatment difficult to perform. Either the stem cells are from the person itself who needs them and is known as autologous stem cell, or they can be received from a donor which is known as an allogeneic stem cell.
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Cells donated by the donor may or may not be accepted by the body’s immune system. Hence, using one’s stem cells reduces the chances of rejection.  In COPD, the tissues and cells of the lungs are destroyed, which causes various types of complications. With stem cell therapy, the destroyed or damaged cells can be regenerated and new lung tissues can be formed. According to the procedure followed by the International Stem Cell Institute (ISCI) in San Diego, California, adipose tissue is removed from the patient and is processed with a combination of platelet-rich plasma. This plasma contains growth factors that help in the process of cell multiplication and development. This helps in COPD treatment because whenever the lungs need repair, about 80% of the stem cells reach the repairing site through the circulatory system. When the blood passes through the lungs, the fresh stem cells get trapped in the space where the damage is and start multiplying and repairing the tissues. The recovery does not take place immediately, but improvement can be noticed in 3 to 6 months. It helps in the suppression of inflammation, improves breathing, and cures many pulmonary complications. Our Nebulized Pure PRP System aims to support this proposition to treat COPD patients.
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Contact our office at (941) 330-8553 to find out more about how Nebulized Pure PRP can offer you relief from symptoms of COPD.