Applications of Mesenchymal stem cell-based therapies in Rheumatoid Arthritis. Applications of Mesenchymal stem cell-based therapies in Rheumatoid Arthritis. Rheumatoid arthritis is chronic autoimmune systematic inflammatory disease of connective tissue with predominant joint disease of erosive-destructive progressive polyarthritis type. The pathogenesis basis of rheumatoid arthritis consist of genetically determined...

Wear and tear of joints and break down of cartilage called osteoarthritis. The pathophysiology of these diseases is complex and characterized by the softening and even distruction of the articular cartilage, with increased matrix degradation due to collagenase and proteoglycanases. The enzymes may be secreted by activated chondrocytes and...

Stem Cells and PRP in Sarasota Florida for Osteoarthritis and as an alternative to Joint Replacment. Abstract INTRODUCTION: Osteoarthritis (OA) is a dynamic process involving the main tissues of the joint for which a global approach should be considered. No disease-modifying OA drug (DMOAD) has yet been approved....

Abstract Over the past two decades, tissue engineering and regenerative medicine have evolved from what many considered a theoretical science to what is now a clinical reality. Tissue engineering combines biomaterial scaffolds, growth factors and stem or progenitor cells to repair damaged tissues. Adipose tissue, an...

There are several characteristics of stem cells that make them unique in comparison with other mammalian cells. First, they exist as unspecialized cells lacking tissue-specific characteristics and they maintain this undifferentiated phenotype until exposed to appropriate signals. Second, they have the capacity for extensive self-renewal....